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Scientific Comments
Rev Bras Hematol Hemoter. 2012;34(5):323-33
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The lost iron is not readily repleted. It has been common
practice for blood centers to recommend iron-rich diets to donors
who have been rejected for low Hb. However, even with excellent
compliance, it requires 6 months or longer to positively impact
ferritin levels
(5)
. Because of this, many researches have prescribed
iron supplementation with good results
(15,19,20)
. However, the
majority of regular blood donors with low or absent iron stores
will never develop IDA
(13)
.
It is important to remember that avoiding unnecessary
deferrals, keeps donors engaged with the blood center
(6)
. In fact,
Boulton demonstrated that only 25% of first-time donors return
to the blood donation facility after rejection, while 47% of first-
time donors come back within 6 months when accepted at their
first visit
(21)
.
Anemia is an important topic for blood donor candidates and
effort has to be made to identify these individuals, prevent iron
depletion in regular blood donors, and engage these individuals
with blood donation.
References
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al. Reasons for blood donation deferral in sub-Saharan Africa: experience
in Ivory Coast. Transfusion. 2012;52(7 Pt 2):1602-6.
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blood, safe blood: can we have both? BMC Med. 2012;10:29.
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M 1st, Leão S, Miranda C, Capuani L, Carneiro-Proitetti AB, Basques F,
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combating malnutrition: World Health Organization; 2000.
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crianca_mulher2006.pdf
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Pereira GA. Etiology of anemia of blood donor candidates deferred by
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hemoglobin in whole blood donors. Ann Hematol. 2012;91(5):775-80.
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microcytosis. Transfus Med. 2010;20(2):88-94. Comment in: Transfus
Med. 2010;20(5):356-7.
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donors. Asian journal of transfusion science. 2008;2(1):9-12.
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Wright DJ, Sacher RA, Gottschall JL, Tobler LH, Simon TL, Nemo
GJ, Schulman J, King MR, Busch MP, Norris P, Rios JA, Benjamin RJ,
Roback JD, Wilkinson SL, Carey PM , Custer BS, Hirschler NV, Triulzi
DJ, Kakaiya RM, Mast AE; NHLBI Retrovirus Epidemiology Donor
Study-II (REDS-II). Iron deficiency in blood donors: the REDS-II Donor
Iron Status Evaluation (RISE) study. Transfusion. 2012;52(4):702-11.
Comment in: Transfusion. 2012;52(6):1382-3; author reply 1383-5.
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The value of routine ferritin measurement in blood donors. Transfusion.
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18. Passos LN, Yurtserver MS, Silva UG, Cordeiro GW, Machado LF, Vasques
F, et al. Sideropenia sem anemia em doadores de sangue do Hemocentro do
Amazonas – Hemoam. Rev Bras Hematol Hemoter. 2005;27(1):48-52.
19. Radtke H, Mayer B, Rocker L, Salama A, Kiesewetter H. Iron
supplementation and 2-unit red blood cell apheresis: a randomized, double-
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20. Radtke H, Tegtmeier J, Rocker L, Salama A, Kiesewetter H. Daily
doses of 20 mg of elemental iron compensate for iron loss in regular
blood donors: a randomized, double-blind, placebo-controlled study.
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donors, with some comments on the relationship to blood supply, and
emphasis on the management of donation-induced iron depletion.
Transfus Med. 2008;18(1):13-27.